Ketamine is an odorless, tasteless drug that is found in liquid, pill, and powder form. Ketamine was developed as an anesthetic for veterinarians to use on animals.Ketamine is classified as a type of disassociative drug. It alters the actions of the neurotransmitter glutamate throughout the brain.Glutamate is involved in perception of pain, responses to the environment, and memory.Chronic use of ketamine may lead to cognitive impairments including memory problems. Users may feel as though their perceptions are located so deep inside the mind that the real world seems distant (hence the use of a "hole" to describe the experience). Some users may not remember this part of the experience after regaining consciousness, in the same way that a person may forget a dream. Owing to the role of the NMDA receptor in long-term potentiation, this may be due to disturbances in memory formation. The "re-integration" process is slow, and the user gradually becomes aware of surroundings. At first, users may not remember their own names, or even know that they are human, or what that means. Movement is extremely difficult, and a user may not be aware that he or she has a body at all.
Risks
Impaired senses, judgment (low doses), coordination, and motor coordination (high doses) / Hallucinations, delirium, and disconnection from surroundings (high doses) / High blood pressure (high doses) / Amnesia (high doses) / Vulnerable to sexual assault (due to loss of control) / Depression (high doses) / Fatal respiratory problems (high doses)